PKRRATING THINGS TO KNOW BEFORE YOU BUY

3B). R526 within the loop involving αJ and αI anchors the C-terminal percentage of the activation loop by forming a salt bridge with E458 at The bottom of αEF. Q459 stabilizes the HRD motif by a hydrogen bond to the primary chain carbonyl of R413. The idea of the activation section is stabilized by a hydrogen bond among Y454 and E480 from αF. w

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